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本文为了进一步验证丙酸睾丸酮（简称丙睾）在药物抗早孕中的作用，使用随机双盲法，将１５１例早孕妇女分为两组，丙睾＋１６，１６－双甲基－反式△２－ＰＧＥ１（简称ＯＮＯ８０２）组，肌注丙睾３００ｍｇ后用ＯＮＯ８０２阴道检１ｍｇ，每６ｈ重复一次，总量为４ｍｇ。对照组使用外观完全相同的安慰剂代替丙睾，ＯＲＯ８０２的用法相同。结果示丙睾＋ＯＮＯ８０２组完全流产，不全流产和失败率分别为７３．３％、１２．０％和１４．７％；对照组为５２．６％、１９．７％和２７．６％（Ｐ＜０．０５）。ＯＮＯ８０２的平均用量分２．３８±１．１９ｍｇ和２．８６±１．１１ｍｇ（Ｐ＜０．０１）。两组引～流时间各为７．Ｚｈ及８．６ｈ，平均流血时间各为１４及１７９。说明丙睾确实能减少前列腺素药物的用量和提高其抗早孕的临床效果。
In order to further verify the role of testosterone propionate in anti-pregnancy, a randomized, double-blind method was used to divide 151 early pregnant women into two groups: testosterone + 16,16-dimethyl-trans2 -PGE1 (referred to as ONO802) group, intramuscular injection of testosterone 300mg ONO802 vaginal seizure 1mg, repeated every 6h, the total amount of 4mg. The control group used exactly the same placebo instead of propranolol, and ORO802 had the same usage. The results showed that the rate of complete abortion, incomplete abortion and failure rate were 73.3%, 12.0% and 14.7% in the testis + ONO802 group and 52.6%, 19.7% and 27.6% in the control group (P <0.05). The average ONO802 dosage was 2.38 ± 1.19 mg and 2.86 ± 1.11 mg (P <0.01). Two sets of cited ~ flow time for each 7. Zh and 8.6h, the average bleeding time of 14 and 179 respectively. Progesterone can indeed reduce the amount of prostaglandin drugs and improve their clinical effect of anti-pregnancy.