论文部分内容阅读
目的：探讨福建省厦门市同安区环境中产毒霉菌分布与原发性肝癌发生的关系。方法：对当地土壤、井水进行霉菌分离鉴定，检测黄曲霉毒素（AF）及杂色曲霉毒素（ST）产生菌株的产毒能力，与各乡镇原发性肝癌死亡率进行相关性比较。结果：在当地环境中检出大量可产生各种致肝癌毒素的霉菌菌株，而且AF及ST产生菌株检出率与各乡镇肝癌死亡率高低相吻合。其中散布着产毒能力极强的黄曲霉菌株，平均AFBI产量为1．88×105ng／g。结论：同安区环境中的产毒霉菌可能是当地原发性肝癌发生的一个致病因素。
OBJECTIVE: To investigate the relationship between the distribution of toxin-producing mold and the occurrence of primary liver cancer in Tongan District of Xiamen City, Fujian Province. Methods: The local soil and well water were used to isolate and identify the fungi, and the aflatoxin (AF)-producing and strain-producing strains were tested for their ability to produce toxins. The correlations between the mortality rates of primary liver cancers in townships and townships were compared. RESULTS: A large number of fungal strains capable of producing various hepatocellular toxins were detected in the local environment, and the detection rates of AF and ST-producing strains were consistent with the level of liver cancer mortality in each township. Among them, an Aspergillus flavus strain with extremely strong toxin-producing ability was distributed, and the average AFBI yield was 1.88×105 ng/g. Conclusion: Toxigenic mold in Tongan district may be a pathogenic factor in the local primary liver cancer.