论文部分内容阅读
依据人疱疹病毒6型(HHV-6)基因组的限制性片段分析,可将该病毒分为甲组和 乙组。甲组病毒仅在成人中检出,尚未证实与任何疾病相关;乙组病毒除确认为幼儿急疹的病原体外,还可能与肺炎、肝炎以及单核细胞增多症样发热性疾病有关。近来有报道表明,某些脑炎患者的发病可能系HHV-6所致。本文作者对病原不明的局灶性脑炎病例进行了回顾性研究,用PCR法检测其脑脊液(CSF)中的HHV-6 DNA,以证明该病毒是否与脑炎的发病有关。
Based on the restriction fragment analysis of the human herpesvirus type 6 (HHV-6) genome, the virus can be divided into groups A and B. Group A virus is detected only in adults and has not been confirmed with any disease; Group B virus in addition to the pathogens identified as young children with acute rash, but also with pneumonia, hepatitis and mononucleosis-like fever-related diseases. Recent reports indicate that the incidence of some encephalitis may be caused by HHV-6. The authors conducted a retrospective study of cases of pathogenic encephalitis of unknown etiology, using PCR to detect HHV-6 DNA in their cerebrospinal fluid (CSF) to demonstrate whether the virus is associated with the onset of encephalitis.