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根据美国肿瘤协会的报道,胰腺癌病人的预后差,总的5年生存率为1～2％,这可能与恶性肿瘤的侵袭性、未能早期诊断以及由于胰腺与其他脏器紧密相邻而难以彻底手术等原因有关。有证据指出,癌肿病人的免疫功能也是影响预后的一个重要因素。作者等观察了41例胰腺癌(28例胰管腺癌,13例腺癌累及壶腹周围和胰腺)手术前的迟发型皮肤超敏反应、促有丝分裂素刺激的淋巴细胞转化反应力、T淋巴细胞和B淋巴细胞计数以及补体水平等。免疫功能检查项目:(1)体外测定淋巴细胞对植物血凝素、刀豆素-A和商陆等促有丝分裂素的反应力。如前两者低于正常对照2个标准差,后者低于正常对照1个标准差,则列为淋巴细胞转化抑制。(2)分别用
According to the American Cancer Society report, the prognosis of patients with pancreatic cancer is poor, and the overall 5-year survival rate is 1-2%. This may be related to the aggressiveness of malignant tumors, failure to diagnose early, and the close proximity of the pancreas to other organs. It is difficult for thorough surgery and other reasons. There is evidence that the immune function of cancer patients is also an important factor that affects the prognosis. The authors observed 41 cases of pancreatic cancer (28 cases of pancreatic duct adenocarcinoma, 13 cases of adenocarcinoma involving the peri-ampullary region and the pancreas) before the delayed-type cutaneous hypersensitivity, mitogenic stimulating lymphocyte transformation response, T lymphocytes Cell and B lymphocyte counts and complement levels. Immune function test items: (1) In vitro determination of lymphocyte response to phytohemagglutinin, concanavalin-A, and pokeweed, etc., to promote mitogen. If the first two are less than 2 standard deviations of the normal control, and the latter is less than 1 standard deviation of the normal control, it is listed as inhibition of lymphocyte transformation. (2) separately