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AP是从蚕蛹中提取的一种多肽物质。有关它的免疫药理作用尚未进行研究。我们发现AP能影响小鼠T淋巴细胞的丝裂原反应性,并能协同IL—2增强T细胞的功能,可能是一种新的免疫调节剂。本文报导AP对T细胞丝裂原反应性的影响,及其与IL—2作用的相互关系。
AP is a polypeptide extracted from silkworm pupae. Its immunopharmacological effects have not been studied. We found that AP can affect the mitogenic reactivity of mouse T lymphocytes and synergize IL-2 to enhance the function of T cells, which may be a new immunomodulator. This article reports the effect of AP on T cell mitogen reactivity and its interaction with IL-2.