饮用咖啡可使血清胆固醇浓度升高。1974年挪威的Bjelke首先发现了此联系并在挪威3个规模较大的研究中得到证实,其中一项研究已发表了详细的研究结果。其他国家的有些研究但不是所有的研究也发现上述联系。两项小的试验提出咖啡(至少以北挪威方式煮沸的咖啡)可能是真正引起胆固醇升高的原因。饮用咖啡也伴有结肠癌发生的危险性减少。Bielke在挪威的162例和美国明尼苏达的259例病例对照研究中的情况也是这样,而且在2项其他病例对照研究也报道了类似的发现。但在另外2项对照研究中未 Drinking coffee can raise serum cholesterol levels. Bjelke first discovered this connection in 1974 in Norway and was confirmed in three large Norwegian studies, one of which published detailed findings. Some studies in other countries but not all the studies also found the above link. Two small trials suggest that coffee (at least in the northern Norwegian way) may actually cause elevated cholesterol. Drinking coffee is also associated with a reduced risk of colon cancer. The same is true of Bielke’s case study of 162 cases in Norway and 259 cases in Minnesota, USA, and similar findings were reported in two other case-control studies. But not in the other two control studies