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目的优选归辛胶囊的最佳提取工艺条件。方法采用L9(34)正交实验设计,以阿魏酸为指标,考察乙醇浓度、提取次数、提取时间及溶剂倍数对提取的影响,优选最佳提取工艺。结果以8倍量65%的乙醇、回流提取1次、每次1.5 h,阿魏酸的得率最高。结论优选出的最佳工艺条件经验证,结果稳定,指标性成分的含量高。
Objective To optimize Guixin capsule extraction conditions. Methods L9 (34) orthogonal design was used. Ferulic acid was used as an index to study the effects of ethanol concentration, extraction times, extraction time and solvent times on the extraction, and the optimal extraction process was optimized. Results 8 times the amount of 65% ethanol, reflux extraction 1, each 1.5 h, ferulic acid yield highest. Conclusion The optimal process conditions are validated, the results are stable and the content of index components is high.