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[目的]观察养正消积胶囊对晚期非小细胞肺癌(NSCLC)化疗的近期疗效、不良反应及生活质量的影响。[方法]将58例患者随机分为两组,治疗组29例采用养正消积胶囊配合GP方案治疗,对照组29例采用GP方案治疗,21天为1周期,完成2周期后评价疗效。[结果]治疗组和对照组的有效率分别为48.30%和44.80%,两组比较差异无显著性意义(P>0.05);治疗组主要毒副反应情况和生活质量情况分别与对照组比较,差异均有显著性意义(P<0.05)。[结论]养正消积胶囊联合化疗治疗晚期非小细胞肺癌可明显降低化疗不良反应发生率,提高患者生活质量。
[Objective] To observe the effect of Yangzheng Xiaoji Capsule in the treatment of advanced non-small cell lung cancer (NSCLC) chemotherapy and the adverse reaction and quality of life. [Method] 58 patients were randomly divided into two groups. The treatment group (n = 29) was treated with Yangzhengxiaoji capsule combined with GP regimen. The control group (n = 29) was treated with GP regimen and the control group was treated with GP regimen for 21 days. [Results] The effective rates of the treatment group and the control group were 48.30% and 44.80%, respectively, with no significant difference between the two groups (P> 0.05). The main side effects and quality of life in the treatment group were compared with those in the control group, respectively. The difference was significant (P <0.05). [Conclusion] Yangzheng Xiaoji Capsule combined with chemotherapy for advanced non-small cell lung cancer can significantly reduce the incidence of adverse reactions and improve the quality of life of patients.