论文部分内容阅读
人类巨细胞病毒(human cytomegalovirus,HCMV)通过多种途径逃避宿主的免疫监视和防御功能，其主要机制为：合成多种时相蛋白，影响和破坏人类白细胞抗原(human leukocyte antigen,HLA)分子在宿主细胞表面的表达，从而干扰抗原递呈及影响NK细胞的杀伤活性。本文就有关最新研究进展作一综述。
Human cytomegalovirus (HCMV) escapes the host immune surveillance and defense functions in a variety of ways. The main mechanisms are: to synthesize multiple phase proteins that affect and destroy human leukocyte antigen (HLA) molecules in Host cell surface expression, thus interfering antigen presentation and affect NK cell killing activity. This article reviews the latest research progress.