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目的 分析重庆地区葡萄球菌引起的感染及耐药状况 ,为葡萄球菌感染的诊疗提供实验依据。方法 收集重庆市 8所医院的 6 5 2株葡萄球菌 ,采用 API- Staph进行分析鉴定。结果 共鉴定出 12种葡萄球菌 ;广泛分布于16类临床标本中 ,其中泌尿生殖道及呼吸道标本中葡萄球菌的分布为最多 ;各类标本中分离到的葡萄球菌以金黄色葡萄球菌、溶血葡萄球菌、表皮葡萄球菌和木糖葡萄球菌较为多见 ;各型葡萄球菌对万古霉素、替考拉宁和氨苄西林 +舒巴坦相对敏感 ,耐药率 <2 0 %,对青霉素、红霉素和四环素耐药率 >80 %。结论 葡萄球菌广泛存在于各类临床标本中 ,可引起全身不同部位的各类感染 ;以前少见的一些葡萄球菌类型成为有意义的感染菌 ;多肽类抗生素应是葡萄球菌感染的首选药物。
Objective To analyze the infection and drug resistance caused by staphylococcus aureus in Chongqing and provide experimental evidence for the diagnosis and treatment of staphylococcal infection. Methods Totally 652 strains of Staphylococcus aureus in 8 hospitals in Chongqing were collected and analyzed by API-Staph. Results A total of 12 staphylococci were identified. Staphylococcus aureus was widely distributed in 16 kinds of clinical samples, of which the distribution of Staphylococcus aureus was highest in urogenital tract and respiratory tract specimens. Staphylococcus aureus isolated from various specimens were staphylococcus aureus, Staphylococcus aureus, Staphylococcus epidermidis and Staphylococcus xylosus are more common; Staphylococcus aureus is relatively sensitive to vancomycin, teicoplanin and ampicillin + sulbactam, the rate of resistance is <20% Su and tetracycline resistance rates> 80%. Conclusion Staphylococcus aureus is widely found in all kinds of clinical samples and can cause various infections in different parts of the body. Some staphylococcal types that were rare before have become meaningful infectious bacteria. Peptide antibiotics should be the drug of choice for staphylococcal infection.