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转化生长因子 (ＴＧＦ)包括ＴＧＦ α和ＴＧＦ β两类 ,ＴＧＦ α的作用是促进细胞增殖 ,ＴＧＦ β为生长抑制因子。1 ＴＧＦ α的结构与功能成熟的ＴＧＦ α是由 50个氨基酸组成的单链多肽 ,其结构、功能与表皮生长因子 (ＥＧＦ)相关。ＴＧＦ α具有与ＥＧＦ相当的亲和力与Ｅ
Transforming growth factor (TGF) includes TGF α and TGF β. The role of TGF α is to promote cell proliferation and TGF β is a growth inhibitory factor. 1 The structure and function of TGF α Mature TGF α is a 50-amino acid single-chain polypeptide whose structure and function are related to epidermal growth factor (EGF). TGF α has an affinity with EGF and E