患者刘某,男性,33岁,工人,河南籍。主诉两下肢走路不稳、僵硬感,经常摔跤,逐渐加重以致不能行走、卧床已1年余。尚有失眠、心慌、语言模糊。近1周来进食发呛、流口水,有时遗尿。患者8岁时得过“黑热病”、“脾大”。1963年患“肝炎”治疗过半年。查体:肝病面容,表情呆板,反应迟钝。面部有蜘蛛痣。心肺未见异常。腹部稍膨隆,有移动性浊音,肝肋下未触及,脾肋下5cm。下肢轻度水肿。神经系统检查:反应迟钝,表情缺乏,瞳孔对光反射存在,调节反应消失。咽反射消失,说话含糊不清。四肢肌张力增强,以两下肢为重,膝反射亢进,踝阵挛阳性,Chardock征阳性,Hoffmann征阳性,Rossolimo征阳性。未见Kayser-Fleischer环。安验室检查:白细胞2900,血红蛋白12.8g%,血小板 Liu patients, male, 33 years old, workers, Henan membership. The main complaint two limbs unsteady, stiff sense of wrestling, and gradually increased so that they can not walk, bed more than 1 year. There are insomnia, palpitation, language ambiguity. Almost a week to eat choking, drooling, and sometimes enuresis. 8-year-old patient had “kala-azar”, “splenomegaly.” 1963 suffering from “hepatitis” treatment for more than six months. Physical examination: liver disease face, facial expression dull, unresponsive. Facial spider mole. Heart and lung no abnormalities. Abdomen slightly bulging, shifting dullness, liver ribs did not touch, spleen ribs 5cm. Lower extremity mild edema. Nervous system examination: unresponsive, lack of expression, pupil light reflex exists, the regulatory response disappeared. Gag reflex disappears, vague. Limb muscle tension increased to both lower extremities, knee hyperactivity, ankle clonus positive, Chardock sign positive, Hoffmann sign positive, Rossolimo sign Zheng positive. No Kayser-Fleischer ring. Laboratory tests: leukocytes 2900, hemoglobin 12.8g%, platelets