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An integrated model,namely the two-equation turbulent model,is introduced to simulate mass transfer in a liquid-solid circulating fluidized bed(LSCFB)riser.Protein desorption is simulated and the pro-posed model is validated.The protein concentration profiles simulated with this model agree well with published experimental results.This model enables direct determination of turbulent mass diffusivity,removing the need to empirically guess a constant turbulent Schmidt number for simulating mass trans-fer in a turbulent flow.This model is useful when the turbulent mass diffusivity is not available for simulating mass transfer in an LSCFB riser.