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血色病是铁在体内沉积过多而致成的一种慢性全身性疾病。有原发性及继发性两种。其发病机理是因铁吸收过多,沉积于各脏器之中而引起脏器功能障碍及纤维性变。血液病患者如长期输血可患输血性(继发性)血色病。本文报告我们收治的8例输血性血色病。临床资料8例均为男性住院患者,年龄20~49岁。其中4例为慢性型再生障碍性贫血(慢性再障),4例为纯红细胞再生障碍性贫血(纯红再障)。入院时再障病程自4个月~2年10个月,治疗后发生血色病病程自6个月~2年。8例中3例存活,5例死亡(死因:1例肝昏迷,2例心衰,2例出院后死亡,其原因不明)。8例均有无力、消化系症状和心悸、心律不齐。发生心力衰竭者6例。有糖尿病表现者4例。性腺功能减退者5例。并发症主要为感染,出血不重,大多为鼻衄或齿龈出血,失血量极少。体检均
Hemochromatosis is a chronic systemic disease caused by excessive deposition of iron in the body. There are two primary and secondary. Its pathogenesis is due to excessive absorption of iron, deposited in the organs which cause organ dysfunction and fibrous changes. Patients with blood diseases such as long-term blood transfusion may have transfusion (secondary) hemochromatosis. This article reports 8 cases of transfusion-induced hemochromatosis. Clinical data of 8 patients were male inpatients, aged 20 to 49 years. Of these, 4 were chronic aplastic anemia (chronic aplastic anemia) and 4 were pure red cell aplasia (pure red aplastic anemia). On admission, aplastic anemia course from 4 months to 2 years and 10 months, the course of hemochromatosis occurred after treatment from 6 months to 2 years. Of the 8 patients, 3 survived and 5 died (cause of death: 1 hepatic coma, 2 heart failure, and 2 deaths after discharge, for unknown reasons). 8 cases were weak, digestive symptoms and palpitations, arrhythmia. 6 cases of heart failure occurred. There are 4 cases of diabetic performance. 5 cases of hypogonadism. Complications mainly for infection, bleeding is not heavy, mostly epistaxis or gingival bleeding, blood loss is minimal. Physical examination are