论文部分内容阅读
研究胸腺肽作为一种免疫增强剂，是否参与调节应激对免疫系统的作用。心理应激采用可控／不可控电击的模型。结果表明，受到6天、每天半小时的可控或不可控的足底电击后，与不受电击的对照组相比，不可控组老年大鼠的免疫功能明显下降，而可控组没有明显变化；肾上腺糖皮质激素的分泌量在受到电台后显著升高。这两个事实说明长期应激对免疫系统造成了破坏作用。腹腔注射胸腺肽（共6次，隔日一次）能颉抗这种变化，改善应激情况下老年大鼠的体液免疫功能，并抑制肾上腺糖皮质激素的上升趋势，说明胸腺肽具有明显的抗应激和抗衰老的作用。
Thymopeptide as an immune enhancer, whether or not involved in the regulation of stress on the immune system. Psychological stress using controlled / uncontrollable shock model. The results showed that the immune function of the uncontrolled group of aged rats was obviously decreased compared with that of the control group without electric shock after controlled by 6 days and half an hour a day, Changes; adrenal glucocorticoid secretion was significantly increased after being radio. These two facts show that long-term stress has a damaging effect on the immune system. Intraperitoneal injection of thymosin (a total of 6 times every other day) can antagonize this change, to improve the stress of the elderly rats humoral immune function and inhibit the upward trend of glucocorticoid adrenal gland, that thymosin has significant anti-stress and Anti-aging effect.