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蓖麻毒素(Ricin)是一种毒蛋白,能抑制蛋白质合成。近年来被用来合成肿瘤导向药物一免疫毒素,在临床应用中仍具有一定的副作用。研究Ricin在细胞内的逆向转运途径有助于其在临床应用中更加完善。本文就Ricin在细胞内的逆向转运途径作一综述。
Ricin is a toxic protein that inhibits protein synthesis. In recent years, it has been used to synthesize a tumor-targeting drug-immunotoxin, which still has certain side effects in clinical application. The study of Ricin’s intracellular reversal transport pathway helps to improve its clinical application. This article reviews the reversal pathway of Ricin in cells.