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目的研究金叶子叶的化学成分。方法利用柱色谱(正相硅胶、RP-18、大孔吸附树脂和SephadexLH-20)、制备HPLC和光谱方法分离鉴定化学成分。结果从金叶子的叶中分离得到10个化合物,分别鉴定为2α,3β,23-trihydroxyurs-5,12-dien-28-oicacid(Ⅰ)、2α,3β,23-trihydroxyurs-12-en-28-oicacid(Ⅱ)、1-O-(β-D-glucopyr-anosyl)-(2S,3S,4R,8Z)-2-[(2′R)-2′-hydroxydocos anoilamino]-8(Z)-octadecene-1,3,4-triol(Ⅲ)、槲皮素-3-O-β-半乳吡喃糖苷(Ⅳ)、槲皮素-3-O-β-D-吡喃葡萄糖苷(Ⅴ)、槲皮素-3-O-α-阿拉伯呋喃糖苷(Ⅵ)、山柰酚-3-α-鼠李吡喃糖苷(Ⅶ)、金叶子毒素-Ⅶ(craibiotoxinⅦ,Ⅷ)、金叶子毒素-Ⅷ(Ⅸ)、proanthocyanidinA-2(Ⅹ)。结论化合物Ⅲ和Ⅴ为首次从该植物叶中获得。
Objective To study the chemical composition of gold leaf leaves. Methods The chemical components were isolated and identified by column chromatography (normal phase silica gel, RP-18, macroporous adsorption resin and Sephadex LH-20), preparative HPLC and spectroscopic methods. Results Ten compounds were isolated from leaves of gold leaves and identified as 2α,3β,23-trihydroxyurs-5,12-dien-28-oicacid(I),2α,3β,23-trihydroxyurs-12-en-28. -oicacid(II), 1-O-(β-D-glucopyr-anosyl)-(2S,3S,4R,8Z)-2-[(2’R)-2’-hydroxydocosanoilamino]-8(Z) -octadecene-1,3,4-triol(III), quercetin-3-O-β-galactopyranoside (IV), quercetin-3-O-β-D-glucopyranoside ( V), quercetin-3-O-α-arabinofuranoside (VI), kaempferol-3-α-rhamopyranoside (VII), golden leaf toxin-VII (craibiotoxin VII, VIII), gold leaf Toxin-VIII(IX), proanthocyanidinA-2(X). Conclusions Compounds III and V were obtained for the first time from the leaves of this plant.