地方性氟中毒是一种生物地球化学性疾病。在高氟地理环境中,由于饮水或食物含氟量高,氟在人体内蓄积,引起以牙齿和骨骼损害为主的全身性慢性毒害。牙齿受损表现为氟斑牙,釉质失去光泽、白斑、着以棕黄或黑褐色,甚者严重磨损、碎裂、折断或早脱。骨骼受损表现为氟骨症,轻者腰腿疼,重者肢体功能障碍,活动受限,四肢变形,肌肉萎缩,弯腰驼背,甚至瘫痪卧床。世界范围内对氟中毒的研究是从本世纪以来开始的,而从古人类化石牙齿上的病变 Local fluorosis is a biogeochemical disease. In a high-fluoride geographical environment, fluoride accumulates in the human body due to the high fluoride content of drinking water or food, causing systemic chronic toxicity mainly of tooth and bone damage. Dental damage manifested as dental fluorosis, enamel luster, white spots, with a brown or dark brown, or severe wear and tear, broken, broken or early off. Skeletal damage manifested as skeletal fluorosis, light waist and leg pain, severe limb dysfunction, limited mobility, limb deformation, muscle atrophy, hunched over, and even paralyzed bed rest. The worldwide study of fluorosis has been from the beginning of this century, and from the lesions on paleontology fossils