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抗高血压药物是中老年人接触较多的一类药物,可导致性功能异常,称药源性性功能障碍,是一种令医生棘手的药源性疾病。由于目前所使用的抗高血压药物多为含两种以上药物的复方制药,因而性功能障碍的发生率也相对增高。因此,在使用这类药物时应谨防引起性功能障碍的不良反应。1、噻嗪类。这类药物中应用最多的是双氢克尿噻,是抗高血压的基础用药。可单独服用,也可与降压药同服,许多治疗高血压的复方制剂中都含有其成份。噻嗪类利尿药所致的性功能障碍,常见为阳痿,其发生率为4％～32％;此外还可引起性欲降低、阴道分泌物减少、早泄等障碍。2、安体舒通。应用安体舒通发生性功能障碍的报道颇多,男性常见的有男性女性化、阳痿、性欲低下;女性有乳腺疼痛性增生、无性欲、月经不规则、阴道分泌物减少。
Antihypertensive drugs are a group of drugs that are more exposed to the elderly and can cause sexual dysfunction, which is called drug-induced sexual dysfunction. It is a drug-induced disease that makes doctors difficult. Due to the current use of antihypertensive drugs are more than two kinds of drugs containing compound pharmaceuticals, so the incidence of sexual dysfunction is also relatively high. Therefore, the use of such drugs should beware of sexual dysfunction caused by adverse reactions. 1, thiazides. The most widely used of these drugs is hydrochlorothiazide, is the basis of antihypertensive medication. Can be taken alone, but also with the antihypertensive drugs with the service, many of the compounds used in the treatment of high blood pressure contains its ingredients. Thiazide diuretics caused by sexual dysfunction, common impotence, the incidence of 4% to 32%; In addition can also cause decreased libido, vaginal discharge reduction, premature ejaculation and other obstacles. 2, spironolactone. Application of spironolactone sexual dysfunction reported quite a lot of men are common male feminization, impotence, low sexual desire; women have breast pain hyperplasia, no sexual desire, irregular menstruation, vaginal discharge decreased.