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麻风肾脏受累的临床表现常可见到,但对其病理损害(特别是可能引起这些表现的肾脏麻风的特异性损害)的确切性质却很少被人注意。大多数作者报告麻风肾脏组织的淀粉样变和所有各型肾炎(如慢性肾盂肾炎、间质性肾炎、慢性弥漫性肾小球肾炎)的发生率概不相同。Powell等报告在15例尸检中仅2例肾脏具有特异性麻风损害(即麻风瘤)。Sainani等报告在60例中有1例具有麻风瘤样损害(但无抗酸杆菌),并提示病期较长的病例发生此种麻风瘤的可能性较大。据报告在印度,麻风病例中有11.2%死于肾功能衰竭。作者对取自50例麻风(瘤型45例、结核样型5例)的肾脏活检组织进
The clinical manifestations of leprosy involvement in the kidney can often be seen, but the exact nature of its pathological damage, particularly of leprosy in the kidney, which may cause these manifestations, is seldom noticed. Most authors report a different incidence of amyloidosis and all types of nephritis (eg, chronic pyelonephritis, interstitial nephritis, and chronic diffuse glomerulonephritis) in leprosy kidney tissue. Powell et al. Reported that only 2 of the 15 autopsies had specific leprosy lesions (ie, leprosy) in the kidneys. Sainani et al. Reported that 1 out of 60 patients had leprosy-like lesions (but no acid-fast bacilli) and suggested that the incidence of such leprosy was greater in longer disease cases. In India, 11.2% of leprosy cases were reported to have died of renal failure. The authors collected from 50 cases of leprosy (tumor 45 cases, 5 cases of tuberculosis samples) of the renal biopsy into