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行鼓室探查术时,常在中耳内见到清亮的液体。此时耳科医生多不关心其来源与成分而将其吸出。实际上中耳内的液体可以是浆液性渗出、粘液性渗出、脑脊液、外淋巴液、注射的液体(即利多卡因)或生理溶液(如盐水)等。为了研究中耳内医源性利多卡因是否存在,作者对液体中利多卡因的含量用酶免疫技术进行了测定。为15例病人行鼓室探查术15次。术前诊断耳硬化症10例,慢性中耳炎伴传导聋3例,先天中耳胆脂瘤1例,外伤性前庭耳蜗神经元炎1例。所有耳鼓膜形态正常。手术时每例病人用1%盐酸利多卡因1.5ml麻醉。注射方式相同:外耳道注1ml,外耳道后上表面
Line tympanometry, often see the clear fluid in the middle ear. At this point, the otolaryngologist does not care about its source and composition and aspirates it. In fact the fluid in the middle ear can be serous exudate, mucoid exudation, cerebrospinal fluid, perilymph, injected liquid (ie, lidocaine) or physiological solution (such as saline) and the like. To investigate the presence of iatrogenic lidocaine in the middle ear, the authors measured the amount of lidocaine in the fluid using enzyme immunoassay. Fifteen patients underwent tympanometry for 15 patients. Preoperative diagnosis of otosclerosis in 10 cases, chronic otitis media with conduction deafness in 3 cases, congenital middle ear cholesteatoma in 1 case, traumatic vestibular cochlear neuritis in 1 case. All eardrums are normal. Each patient during surgery with 1% lidocaine hydrochloride 1.5ml anesthesia. The same way of injection: 1ml external auditory canal, external auditory canal after the upper surface