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目的回顾性分析大脑胶质瘤病磁共振成像(MRI)及磁共振波谱(MRS)特点,以探讨其对本病诊断的临床价值。方法综合7例患者的临床表现、影像学特点及病理诊断,均符合大脑胶质瘤病诊断标准。常规行SE序列平扫及增强。其中3例行MRS研究,二维多体素、点分辨法(PRESS)、TE144ms。结果所有病例均侵犯2个脑叶或以上。病变区呈长T2、稍长T1异常信号,受累区脑组织肿胀,占位效应轻。增强扫描3例见小结节或片状强化,4例无明显强化。3例MRS表现均有不同程度NAA降低,Cho上升,Cho/Cr和Cho/NAA的比值上升。结论MRI是目前诊断大脑胶质瘤病的首选影像学方法,MRS对于鉴别诊断有较大价值。
Objective To retrospectively analyze the features of magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) of gliomas in order to investigate its clinical value in the diagnosis of this disease. Methods The clinical manifestations, imaging features and pathological diagnosis of 7 patients were all consistent with the diagnostic criteria of gliomatosis. Conventional line SE sequence scan and enhancement. Three of them performed MRS study, two-dimensional multi-voxel, point-resolution method (PRESS), TE144ms. Results All cases were violations of two lobes or more. Lesions showed a long T2, slightly longer T1 abnormal signal, affected brain tissue swelling, placeholder effect light. Enhanced scan in 3 cases, see the small nodules or sheet enhancement, 4 cases without significant enhancement. NAA decreased, Cho increased and Cho / Cr and Cho / NAA increased in 3 cases of MRS. Conclusion MRI is the imaging method of choice for the diagnosis of gliomatosis. MRS is of great value in the differential diagnosis.