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作者用肠溶衣聚合物 Eudragit L1 0 0 - 5 5和羧甲基乙基纤维素 (CMEM)作稳定剂制备新型的聚丙交酯 -乙交酯 (PLG)微粒作为口服疫苗释放载体 ,微粒表面包有肠溶衣以保护蛋白。同时 ,以传统的表面活性剂聚乙烯醇 (PVA)制备的微粒作为对照。结果显示用上述 3种表面活性剂稳定的载
The authors used the enteric-coated polymers Eudragit L1 0 0-55 and carboxymethyl ethyl cellulose (CMEM) as stabilizers to prepare novel polylactide-glycolide (PLG) microparticles as an oral vaccine release carrier. The surface of the microparticles Enteric coated to protect the protein. At the same time, the traditional surfactant PVA (polyvinyl alcohol) prepared particles as a control. The results show stable loading with the above three surfactants