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目的:探讨血色病的腹部影像学的特征,评价腹部影像学、肝脏活检组织病理学检查在血色病诊断中的作用。方法:回顾分析4例诊断为血色病临床资料完整的患者,对其腹部影像学、病理组织学和特殊染色的特点进行分析。结果:遗传性血色病3例,继发性血色病1例,2例CT扫描肝脏及脾脏均呈显弥漫性增大,肝脏及脾脏密度呈弥漫性增高1例,肝脏密度正常1例,胰腺密度均正常。T2WI肝脏呈低信号4例,脾脏呈均匀低信号3例,呈“胡椒盐”样低信号1例,胰腺信号减低3例。T1WI肝脏呈低信号4例,脾脏呈低信号3例,呈“胡椒盐”样低信号1例,胰腺信号减低3例。伴有少量胸腔及腹腔积液1例。1例肝脏组织活检HE染色及普鲁士蓝染色见大量铁沉积,另1例见少量铁沉积。结论:血色病的MRI及CT的表现都具有特征性征象,但MRI较CT的表现更具有特异性,MRI的T2WI呈低信号是诊断本病的特异性征象,肝脏组织活检是诊断本病的金标准。
Objective: To investigate the features of abdominal imaging of hemochromatosis and to evaluate the role of abdominal imaging and liver biopsy histopathology in the diagnosis of hemochromatosis. Methods: The clinical data of 4 cases diagnosed as hemochromatosis were retrospectively analyzed. The characteristics of abdominal imaging, histopathology and special staining were analyzed. Results: 3 cases of hereditary hemochromatosis, 1 case of secondary hemochromatosis, 2 cases of CT scan of liver and spleen were significantly increased diffusely, liver and spleen density was diffusely increased in 1 case, normal liver density in 1 case, the pancreas The density is normal. There were 4 cases of low signal in T2WI liver, 3 cases of low signal in spleen, 1 case of low salt signal in pepper salt and 3 cases of decrease in pancreatic signal. 4 cases showed low signal in T1WI liver, 3 cases showed low signal in spleen, 1 case showed low signal of pepper salt and 3 cases of decreased pancreatic signal. 1 case with a small amount of pleural and ascites. One case of liver biopsy HE staining and Prussian blue staining to see a large number of iron deposition, and the other case of a small amount of iron deposition. CONCLUSIONS: The manifestations of hemochromatosis in MRI and CT all have characteristic signs, but MRI is more specific than CT. The low signal of T2WI in MRI is the specific sign to diagnose this disease. Liver biopsy is the diagnosis of this disease gold standard.