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目的 探讨一般女性人群中妊娠高血压综合征(PIH)发病的危险因素及各危险因素间的相互作用。方法 共3205名孕妇接受筛检,其中219例诊断为PIH,研究数据通过问卷调查和测量得到。用非条件logistic回归分析探讨PIH发生的危险因素。结果 单因素分析显示:年龄、家庭收入与PIH的发生有关联;高血压家族史增加PIH发生的危险。经产史、自然流产次数增加了孕妇发生PIH的危险;高孕中体重增加了孕妇发生PIH的危险。多因素分析表明:年龄(OR=1.801,95%CI:1.106~2.934)、高血压家族史(OR=3.599,95%CI:1.862~6.947)、自然流产次数(OR=8.955,95%CI:4.118~19.427)、孕中体重(OR=3.062,95%CI:1.619~5.905)是PIH发生的危险因素。结论 加强对年龄大、自然流产次数多、有高血压家族史、高孕中体重的孕妇的检查,以预防PIH的发生。
Objective To investigate the risk factors of pregnancy induced hypertension (PIH) and the interaction among risk factors in general female population. Methods A total of 3205 pregnant women were screened, of whom 219 were diagnosed as PIH. The data were obtained through questionnaire and measurement. Non-conditional logistic regression analysis of PIH risk factors. Results Univariate analysis showed that age and family income were associated with the occurrence of PIH. Family history of hypertension increased the risk of PIH. The history of birth, the number of spontaneous abortion increases the risk of PIH pregnant women; high pregnancy weight gain pregnant women increased the risk of PIH. Multivariate analysis showed that the age (OR = 1.801, 95% CI: 1.106-2.934), family history of hypertension (OR = 3.599,95% CI: 1.862-6.947), number of spontaneous abortion (OR = 8.955,95% CI: 4.118 ~ 19.427). Pregnancy body weight (OR = 3.062, 95% CI: 1.619-5.905) was a risk factor for PIH. Conclusion To strengthen the examination of pregnant women with large number of spontaneous abortion, high family history of hypertension and high pregnancy, so as to prevent the occurrence of PIH.