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目的：观察严重烧伤病人巨细胞病毒(HCMV)感染情况及对病情的影响。方法：采用PCR技术检测50例烧伤病人创面及尿液中HCMV-DNA，用ELISA法观察血清中HCMV-IgM、IgG,并与50例正常者检测结果进行对照。结果：观察组血清中HCMV-IgM和创面及尿液中HCMV-DNA均高于对照组，感染HCMV的烧伤病人创面愈合较慢，外周血中淋巴细胞计数较高。结论：烧伤患者感染HCMV的机会较大，且烧伤后早期的感染机会大于后期。PCR技术检测HCMV感染较为敏感而特异。“,”Objective: To observe human cytomegalovirus (HCMV) infection in severely burned patients and its influence on case conditions. Method: HCMV-DNA level in wound, urine and serum samples from 50 severely burned patients and 50 healthy persons (as control) were examined by using PCR technique and HCMV-IgM, IgG levels by using ELLSA method. Results: All the results indicated that the positive rate of infection in severely burned patients was significantly higher than that of the control. Wound healing of the HCMV infected patients was slower than those without infection. Lymphocyte counts in peripheral blood in infected patients were higher than those without infection. Conclusion: Burn patients are susceptible to HCMV infection, especially at the early stage of burn.