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内皮素-1可能作为一种重要的炎症介质参与哮喘的发病过程,作者概述其在气道炎症及气道重建形成中的作用及途径,以阐明ET-1在哮喘病理生理过程中的重要地位。
Endothelin-1 may participate in the pathogenesis of asthma as an important inflammatory mediator. The author summarizes the roles and pathways of ET-1 in airway inflammation and airway remodeling to clarify the important role of ET-1 in the pathophysiology of asthma .