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疱疹性角膜炎是致盲的重要原因,自从使用碘脱氧尿苷(IDU),使疗效有了很大的改观,近十多年,新的抗病毒药物陆续出现,药物的生化作用原理也渐趋明瞭,新药中如三氟胸苷、阿糖腺苷等,也有良好疗效。药物抗病毒主要通过:(1)阻止病毒吸附及穿入细胞,(2)抑制病毒核酸基因组的复制,(3)抑制病毒蛋白质的合成,(4)通过机体发挥抗病毒作用等方式。在干扰病毒繁殖时,也会损害正常组织。单疱病毒是属于DNA病毒,在寻求理想的抗单疱病毒药物时,以能选
Herpes keratitis is an important cause of blindness, since the use of iodine deoxyuridine (IDU), so that the efficacy has been greatly improved over the past decade, new anti-viral drugs one after another, the principle of biochemical drugs gradually Daming, new drugs such as trifluorothymidine, vidarabine, also have good effect. Drug antivirus mainly through: (1) to prevent the virus adsorption and penetration into cells, (2) inhibition of viral nucleic acid genome replication, (3) inhibition of viral protein synthesis, (4) through the body to play antiviral effects and other means. When interfering with virus propagation, it can also damage normal tissues. Herpes simplex virus is a DNA virus, in the search for the ideal anti-herpes simplex virus drugs, to be able to elect