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目的了解北京市区无偿献血者梅毒传染指标流行情况,为无偿献血的招募策略调整提供依据。方法分析2007年1月1日～2011月12月31日北京市红十字血液中心无偿献血者抗梅毒螺旋体的检测结果,按性别、年龄、职业、文化程度、献血方式、献血组织形式进行分层,回顾性调查分析各层5年间的整体情况。结果 2007～2011年5年间北京市红十字血液中心1 065 177人次无偿献血者梅毒抗体筛查阳性者4923例,阳性率为0.462%;女性的阳性筛查率高于男性(χ2=27.84,P<0.05);梅毒抗体阳性检出率随着年龄增长而增加,不同年龄层之间差异有统计学意义(P<0.05);5种职业献血人群的阳性率间差异有统计学意义(P<0.05),不合格率排序为农民>其他>工人>职员>学生;不同文化程度、不同献血形式以及不同献血组织形式献血人群的检测结果差异均有统计学意义(P<0.05),机采项目的抗梅毒螺旋体检测阳性率高于全血,高中以下人群和家庭互助人群的阳性率最高。结论献血者选择过程的质量控制是招募安全血源的重要环节,根据本地献血人群的特点,应选择低危的、具有较高文化程度的年轻人和学生,积极引导他们成为固定献血者。同时,提高检测效能进一步保证血液安全。
Objective To understand the prevalence of syphilis infection in unpaid blood donors in Beijing and to provide evidence for the adjustment of recruitment strategies for unpaid blood donation. Methods The results of anti-Treponema pallidum test of unpaid blood donors in Beijing Red Cross Blood Center from January 1, 2007 to December 31, 2007 were stratified by sex, age, occupation, educational level, blood donation and blood donation , Retrospectively surveyed and analyzed the overall situation of all levels in five years. Results 4923 cases of syphilis antibody positive were found in 1 065 177 blood red blood centers in Beijing from 2007 to 2011. The positive rate was 0.462%. The positive rate of female screening was higher than that of male (χ2 = 27.84, P <0.05). The positive rate of syphilis antibody increased with age and the difference was statistically significant (P <0.05). There was significant difference among the five occupational blood donors (P < 0.05). The failure rate was ranked as peasant> other> workers> staff> students. There were significant differences in test results between blood donation groups with different educational level, different forms of blood donation and different forms of blood donation (P <0.05) The positive rate of anti-Treponema pallidum test was higher than that of whole blood, and the highest positive rate was found in the following groups of high school children and the family mutual aid crowd. Conclusion The quality control of blood donator selection process is an important part of recruiting safe blood source. According to the characteristics of local blood donors, young people and students at low risk and high education level should be selected and actively guide them to be fixed blood donors. At the same time, improve test efficiency to further ensure blood safety.