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目的:研究氨基酮戊酸光动力疗法(Amino ketones pentanoic acid kinetics of light therapy,ALA-PDT)联合CO_2激光治疗宫颈尖锐湿疣的临床疗效。方法:将选中的50例宫颈尖锐湿疣患者分为治疗组和对照组,治疗组使用ALA-PDT结合CO_2激光治疗,对照组只采用CO_2激光治疗,对比两组治疗率和复发率。结果:治疗组治愈率达88%,对照组治愈率为32%,治疗组疗效明显好于对照组,两组差异明显有统计学意义(P<0.05);术后随访观察复发率,治疗组未复发率为80%,对照组未复发率为40%。结论:光动力联合CO_2治疗宫颈尖锐湿疣有良好效果,治愈率高、复发率低、安全性高。
Objective: To study the clinical efficacy of Amino ketones pentanoic acid kinetics of light therapy (ALA-PDT) combined with CO_2 laser treatment of cervical condyloma acuminatum. Methods: The selected 50 patients with cervical condyloma acuminatum were divided into treatment group and control group. The treatment group was treated with ALA-PDT combined with CO 2 laser. The control group was treated with CO 2 laser only. The treatment rate and recurrence rate were compared between the two groups. Results: The cure rate was 88% in the treatment group and 32% in the control group. The curative effect in the treatment group was significantly better than that in the control group, with significant difference between the two groups (P <0.05). The recurrence rate was observed and followed up in the treatment group No recurrence rate was 80%, the control group, the recurrence rate was 40%. Conclusion: Photodynamic therapy combined with CO_2 has a good effect on cervical condyloma acuminata, with high cure rate, low recurrence rate and high safety.