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我院自制的顺铂用于治疗晚期原发性恶性卵巢肿瘤32例。均经手术和病理证实。上皮类占23/32。本文介绍了顺铂使用方法,毒性和近期疗效。顺铂辅佐手术治疗使16/32的晚期病人获得完全效应。按寿命表法分析,5年存活率为20.8％。毒性较轻,主要是胃肠道反应。血象变化不大。也未见明显的肾毒现象发生。
Cisplatin homemade in our hospital was used to treat 32 patients with advanced primary malignant ovarian tumors. All confirmed by surgery and pathology. Epithelial class accounted for 23/32. This article describes the use of cisplatin, toxicity and short-term efficacy. Cisplatin-assisted surgical treatment resulted in complete effects in 16/32 patients with advanced disease. According to the life table analysis, the 5-year survival rate was 20.8%. Less toxic, mainly gastrointestinal reactions. Little change in blood. No obvious nephrotoxicity occurred.