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目的对３６个冷冻胚胎移植周期的治疗做一临床分析。方法用药方案包括自然周期、激素替代周期间（ＨＲＴ）和克罗米芬或人绝短期促性腺激素（ＨＭＧ）刺激周期，第２天胚胎于出现尿黄体生成素（ＬＨ）峰或给予黄体酮的第３－４天移植，第３天胚胎于出现尿ＬＨ峰或给予黄体酮的第４～５天移植。结果 ３６例患者进行了３６个周期的冷冻胚胎移植，每周期移植胚胎数（３．５±１．４）个，３６个移植周期中１０次临床妊娠（２７．８％），３例双胎妊娠（ １例于孕中期自动减为单胎）， ７例单胎． ２例妊娠早期自然流产．有 ８例继续妊娠达 ７－３５周。原核期冻融 ５个周期，获临床妊娠 ３次，胚胎期冻融３１个周期，获临床妊娠７次，移植第２天胚胎：于出现尿ＬＨ峰后第４天移植的１０个周期中，１次妊娠：第３天移植的１个周期获妊娠；第２天胚胎于出现尿ＬＨ峰后第４天移植的１６个周期中，５次妊娠；第５天移植的１个周期中，无妊娠。于用黄体酮第４天移植的１周期中无妊娠，第５天移植的３个周期中２次妊娠。结论冻融胚胎移植能获得满意的妊娠率。第２天冻融胚胎的最佳移植时机为出现尿ＬＨ峰的第３大，第３天冻融胚胎为出现尿ＬＨ峰的第４天或于激素替代治疗（ＨＲＴ）周期用黄体酮第５天。
Objective To analyze the treatment of 36 frozen embryo transfer cycles. Methods The drug regimen consisted of natural cycle, hormone replacement cycle (HRT) and clomiphene citrate or human short-term gonadotropin (HMG) stimulation cycle. On day 2 embryos were exposed to LH test or progesterone Transplantation was performed on days 3-4, and embryos on day 3 were transplanted on the 4th to 5th day when urinary LH peak or progesterone administration occurred. RESULTS: Thirty-six patients underwent 36 cycles of frozen embryo transfer with 3.5 ± 1.4 embryos per cycle, 10 clinical pregnancies (27.8%) over 36 cycles and 3 twin pregnancies Pregnancy (1 in the second trimester automatically reduced to singleton), 7 singletons. 2 cases of early pregnancy spontaneous abortion. There are 8 cases of pregnancy continued for 7-35 weeks. Prokaryotic freeze-thaw cycle of 5, clinical pregnancy 3 times, 31 cycles of embryonic freeze-thaw cycles, clinical pregnancy 7 times, 2 days embryo transfer: urine urine LH peak 4 days after transplanting 10 cycles, 1 pregnancy: one cycle of pregnancy was grafted on day 3; 5 pregnancies in 16 cycles of day 4 embryo transfer on day 2 after urine LH peak; and none on 1 day of transplant on day 5 Pregnancy. There were no pregnancies in one cycle of transplantation with progesterone on day 4 and two pregnancies in the three cycles of day 5 transplantation. Conclusion Frozen-thawed embryo transfer can achieve a satisfactory pregnancy rate. On the second day, the best time for transplanting embryos was the third day of urine LH peak, the third day of freeze-thaw embryo was the day 4 of urine LH peak or the fifth day of hormone replacement therapy (HRT) day.