目的 :了解无锡市中老年妇女血浆叶酸水平。方法 :以年龄在 35～ 6 4岁 ,分别来自城区和农村的 6 2 3名妇女为研究对象 ,对其血浆叶酸水平进行统计学分析。结果 :研究人群血浆叶酸平均水平为 2 0 .5 nmol/ L ,平均叶酸缺乏率为 1.8% ,城区妇女血浆叶酸平均水平高于农村妇女 ,冬春季节血浆叶酸水平高于夏秋季节。结论 :无锡市中老年妇女血浆叶酸水平高于我国北方地区妇女 ,城区与农村、冬春季节与夏秋季节中老年妇女血浆叶酸水平有非常显著性差异。 Objective: To understand the level of plasma folate in middle-aged and elderly women in Wuxi. Methods: A total of 623 women, aged 35-6 4 years old, from urban and rural areas, were selected as the study subjects, and their plasma folate levels were analyzed statistically. Results: The study population average folate level of 20.5 nmol / L, the average folic acid deficiency rate of 1.8%, urban women’s average plasma folate levels higher than rural women, winter and spring plasma folic acid levels higher than the summer and autumn. Conclusion: The level of plasma folate in middle-aged and elderly women in Wuxi is higher than that of women, urban and rural areas in northern China. There is a significant difference in plasma folate levels between middle-aged and elderly women in winter, spring and summer.