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目的:研究阿奇霉素在儿科临床应用过程中的不良反应。方法:选取本院自2012年1月~2014年1月间收治的400例患儿进行临床分组研究阿奇霉素应用的不良反应,对其进行随机分组,分为对照组和观察组,200例/组,对照组采用静脉滴注阿奇霉素进行治疗,观察组则采用口服阿奇霉素进行治疗,对比分析两组患者的临床不良反应结果:两组患者之间出现的主要不良反应有过敏性皮疹、过敏性休克、胃肠道不良反应以及发热等症状,此两组患者之间出现的不良反应之间无显著性差异(P>0.05),无统计学意义。结论:根据本次静脉滴注和口服进行分组临床调查,其主要的不良反应有肠胃不适、过敏性休克、过敏性皮疹以及发热等症状。因此这类不良反应病情较急,在使用阿奇霉素的时候要注意其不良反应症状,需要及时的采取措施来进行预防不良反应。
Objective: To study the adverse reactions of azithromycin in pediatric clinical application. METHODS: A total of 400 children admitted to our hospital from January 2012 to January 2014 were enrolled in this study. Adverse reactions to azithromycin were randomly divided into control group and observation group, 200 cases / group , The control group was treated with intravenous azithromycin, the observation group was treated with oral azithromycin, the clinical adverse reactions were compared between the two groups of patients: the main adverse reactions between the two groups were allergic rash, anaphylactic shock, Gastrointestinal adverse reactions and fever and other symptoms, there was no significant difference between the two groups of adverse reactions (P> 0.05), no statistical significance. Conclusion: According to this intravenous drip and oral group clinical investigation, the main adverse reactions are gastrointestinal discomfort, anaphylactic shock, allergic rash and fever and other symptoms. Therefore, the more acute adverse reactions such conditions, the use of azithromycin should pay attention to the symptoms of adverse reactions, the need for timely measures to prevent adverse reactions.