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能够准确证明是单纯疱疹病毒2型(HSV-2)而非HSV-1感染的血清学方法的建立以及HSV PCR方法的建立,为阐明HSV感染的发病机理和流行病学增加了新的见解。近来的血清流行病学研究表明,HSV-2抗体存在于25％去综合医院看病的患者、30％～40％产科人群、40％～80％异性恋STD就诊者和60％～80％HIV感染者。然而有一些研究表明,大多数血清阳性而无生殖器溃疡病史者是由于缺乏对感染症状和体征的认识,在妇女中如果对病人进行教育可以增加她们对生殖器损害的识别能力。最近一项对亚临床排毒研究提示,泌尿生殖
The establishment of a serological method that can accurately prove HSV-2 but not HSV-1 infection as well as the establishment of HSV PCR methods add new insights into elucidating the pathogenesis and epidemiology of HSV infection. Recent seroprevalence studies have shown that HSV-2 antibodies are present in 25% of patients going to a general hospital, 30-40% of obstetric people, 40-80% of heterosexual STD patients and 60-80% of HIV infections By. However, some studies have shown that the majority of patients with positive seropositivity without a history of genital ulcers are due to a lack of awareness of the symptoms and signs of infection and that their ability to recognize genital lesions may be increased if women are educated. A recent study of subclinical detoxification prompted genitourinary