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采用小鼠完全福氏佐剂气囊法及二硝基氟苯(DNFB)诱导小鼠迟发性超敏反应(DTH)等法,观察培本方对T淋巴细胞介导的免疫性炎症的作用,探明培本方防治哮喘的作用原理。结果表明:培本方能明显抑制小鼠肉芽重量、渗出液、白细胞数、血管增生;能抑制小鼠迟发性超敏反应所致的炎性水肿。
The effects of Pei-fang on T-lymphocyte-mediated immune inflammation were observed by mouse complete Freund’s adjuvant balloon method and dinitrofluorobenzene (DNFB) induced delayed-type hypersensitivity (DTH) in mice. , Exploring the principle of action of Pei Fang in the prevention and treatment of asthma. The results showed that:Peibenfang can significantly inhibit the mice’s granulation weight, exudate, white blood cell count, vascular proliferation, and can inhibit the inflammatory edema caused by delayed hypersensitivity in mice.