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在全身抗痨治疗的同时,配合椎管内注射抗痨药物及激素治疗结核性脑膜炎(简称“结脑”),在临床上已广泛使用。但椎管内注射常规剂量INH及地塞米松引起的不良反应报道较少,笔者曾遇两例,报道如下: 例1,女性,27岁,农民,因发热,头痛,呕吐40天,于1989年8月30日入院,无精神病史。查体:神志清,双眼瞳孔等大,对光反射存在,颈部抵抗、神经系(一)。脑脊液化验符合结脑改变。诊断:结脑。采用KHRE四联化疗。4月4日上午腰穿,压力1.9kPa,椎管内注射INH50mg+地塞米松2mg,3小时后患者出现精神恍惚,烦
In systemic anti-tuberculosis treatment at the same time, with intraspinal injection of anti-tuberculosis drugs and hormone therapy of tuberculous meningitis (referred to as “knot brain”), has been widely used in clinical practice. However, intra-spinal injection of INH and dexamethasone regular dose of adverse reactions caused by less reported, I have encountered two cases, reported as follows: Example 1, female, 27 years old, due to fever, headache, vomiting 40 days in 1989 Admission on August 30, no history of mental illness. Examination: Consciousness, pupils and other large eyes, there is light reflection, neck resistance, nervous system (a). Cerebrospinal fluid test in line with changes in the brain. Diagnosis: knot brain. KHRE quadruple chemotherapy. 4 月 4 morning waist wear, pressure 1.9kPa, INH50mg spinal dexamethasone injection 2mg, 3 hours after the patient appeared trance, annoying