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目的对布鲁菌感染患者降钙素原(PCT)、C-反应蛋白(CRP)、白细胞计数(WBC)、血沉(ESR)进行研究。方法将169例血培养阳性患者分为3组,其中布鲁菌组39例、大肠埃希菌组81例、金黄色葡萄球菌组49例,分别对3组PCT、CRP、WBC、ESR的检测结果进行比较。结果 PCT在3组中比较,布鲁菌组均低于大肠埃希菌组和金黄色葡萄球菌组,差异有统计学意义(P<0.05);金黄色葡萄球菌组低于大肠埃希菌组,差异有统计学意义(P<0.05)。WBC在3组中比较,布鲁菌组均低于大肠埃希菌组和金黄色葡萄球菌组,差异有统计学意义(P<0.05);大肠埃希菌组和金黄色葡萄球菌组,差异无统计学意义(P>0.05)。CRP、ESR检测结果比较,差异无统计学意义(P>0.05)。结论血清PCT水平在布鲁菌感染患者中升高不明显,联合CRP、WBC、ESR等指标可以辅助诊断布鲁菌血流感染。
Objective To study the expression of procalcitonin (PCT), C-reactive protein (CRP), white blood cell count (WBC) and erythrocyte sedimentation rate (ESR) in patients with Brucella infection. Methods 169 cases of blood culture positive patients were divided into 3 groups, including 39 cases in Brucella group, 81 cases in Escherichia coli group and 49 cases in Staphylococcus aureus group. The detection of PCT, CRP, WBC and ESR The results are compared. Results PCT in the three groups, Brucella group were lower than those in Escherichia coli and Staphylococcus aureus group, the difference was statistically significant (P <0.05); Staphylococcus aureus was lower than the Escherichia coli group , The difference was statistically significant (P <0.05). WBC in the three groups, Brucella group were lower than the Escherichia coli group and Staphylococcus aureus group, the difference was statistically significant (P <0.05); Escherichia coli group and Staphylococcus aureus group, the difference No statistical significance (P> 0.05). CRP, ESR test results, the difference was not statistically significant (P> 0.05). Conclusions The level of serum PCT is not significantly elevated in patients with Brucella infection. The combination of CRP, WBC, ESR and other indicators may be helpful in the diagnosis of brucellosis infection.