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目的调查1例人感染H7N9禽流感病例,总结疫情防控工作经验。方法对病例和密切接触者进行个案调查与分析,采用实时荧光定量PCR检测病例咽拭子H7N9禽流感病毒核酸作确诊。结果患者以发热为首发症状,继而出现咳嗽、咳痰和左下肺炎,伴有高血压、糖尿病等基础性疾病,实时荧光定量PCR检测病例咽拭子H7N9禽流感病毒核酸阳性。经达菲等抗病毒治疗,康复出院。患者发病前7 d内曾去过农贸市场。密切接触者50人,均未出现流感样症状,血清H7N9禽流感HI抗体均为阴性。结论该病例以发热肺炎为主要临床特征,感染来源未明,不能排除农贸市场禽类区暴露的可能,未发现人传人情况。
Objective To investigate a case of H7N9 bird flu and summarize the experience of epidemic prevention and control. Methods Cases and close contacts were investigated by case analysis and confirmed by real-time fluorescence quantitative PCR for detection of throat swab H7N9 avian influenza virus nucleic acid. Results The patients developed fever as the first symptom, followed by cough, sputum and left lower pneumonia, accompanied with hypertension, diabetes and other basic diseases. The real-time fluorescent quantitative PCR detected the throat swab H7N9 avian influenza virus nucleic acid positive. Antiviral therapy such as Tamiflu, rehabilitation discharged. The patient had visited the farmer’s market within 7 days before onset. Close contact with 50 people, no flu-like symptoms, serum H7N9 bird flu HI antibody were negative. Conclusion The case of fever pneumonia as the main clinical features, the source of infection is not clear, can not rule out the possibility of exposure to poultry markets farmers market, did not find the situation of human transmission.