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目的探讨精神分裂症患者快感缺失与童年创伤经历的关系。方法采用中文版修订社会快感缺失量表(RSAS-C)、中文版修订躯体快感缺失量表(RPAS-C)和童年创伤问卷(CTQ)对198例精神分裂症患者和271例正常健康者进行评估,分析快感缺失与童年创伤间的关系。结果患者组RSAS-C评分(13.32±6.12)、RPAS-C评分(19.04±8.53)、CTQ总分(47.63±13.49)及其各因子分均显著高于正常组(分别为10.40±5.05,16.80±7.89,38.82±10.05),差异有统计学意义(P<0.05);患者组RSAS-C评分、RPASC评分与阳性与阴性症状量表(PANSS)总分及阴性症状分均呈正相关(rs=0.266~0.439,P<0.01);患者组RSAS-C评分(rs=0.419,P<0.01)和RPAS-C评分(rs=0.322,P<0.01)与CTQ总分呈正相关,控制PANSS总分后,快感缺失评分与童年创伤评分间的相关性仍存在。结论精神分裂症患者快感缺失程度较高,与童年创伤经历之间存在关联,提示早年的创伤经历可能会影响个体对躯体及社会交往快乐的体验能力。
Objective To explore the relationship between the loss of pleasure and childhood traumatic experience in schizophrenia patients. Methods A total of 198 schizophrenia patients and 271 normal controls were enrolled in this study. The Chinese version of RSAS-C, RPAS-C and CTQ were used in this study. To assess and analyze the relationship between loss of pleasure and childhood trauma. Results The scores of RSAS-C (13.32 ± 6.12), RPAS-C (19.04 ± 8.53), CTQ (47.63 ± 13.49) and their scores in all patients were significantly higher than those in the normal group (10.40 ± 5.05 and 16.80 ± 7.89,38.82 ± 10.05), the difference was statistically significant (P <0.05). There was a positive correlation between RSAS-C score, RPASC score and total score and negative symptom score of PANSS (rs = 0.266-0.439, P <0.01). The RSAS-C score (rs = 0.419, P <0.01) and RPAS-C score (rs = 0.322, , There is still a correlation between pleasure loss score and childhood trauma score. Conclusions The high degree of loss of pleasure in patients with schizophrenia is associated with the childhood traumatic experience, suggesting that the traumatic experience of the early years may affect the individual ’s ability of experiencing the joy of physical and social interaction.