中毒性休克综合征(Toxic shock syndromc, TSS)是一种由葡萄球菌所致的严重临床体征的疾病.1978年由美国Todd首先报告,其共患特点为高热、头痛、结膜充血、猩红热样红斑、浮肿、呕吐、水样腹泻、肾功能衰竭、肝脏损害,广泛性血管内凝集,进而形成多种体征的重度迁延性休克死亡.从患者的鼻咽部、阴道、气管粘膜和化脓病灶分离出金黄色葡萄球菌,但血培养阴性.根据 Toxic shock syndrome (TSS) is a serious clinical sign of staphylococcal disease caused by stool in 1978 by the United States first reported Todd, its comorbid characteristics of high fever, headache, conjunctival congestion, scarlet fever-like erythema , Edema, vomiting, watery diarrhea, renal failure, liver damage, extensive intravascular coagulation, and the formation of a variety of signs of severe delayed shock death from the patient’s nasopharyngeal, vaginal, tracheal mucosa and purulent lesions were isolated Staphylococcus aureus, but blood culture is negative