反复应用同一种或相类似的药物时,某些生物反应愈来愈弱以至完全消失。这种急性耐受現象被Champy与Glcy称为“快速防护”(Tachyphylaxie,按希腊語:Tachy=快速,Phylaxie=保护性)。动物机体对許多药物都能产生急性耐受。以往学者对于发生耐受的原因以及影响耐受发生的因素等問題,意見很不一致。1928年陈克恢提出“受点阻断”学說以解释麻黃硷的急性耐受,这个假說曾获得許多学者的支持。此外,还有一些 Repeated use of the same or similar drugs, some of the biological response is weaker and even disappear completely. This type of acute tolerance is referred to by Champy and Glcy as Tachyphylaxie (in Greek: Tachy = fast, Phylaxie = protective). Animal body can produce acute tolerance to many drugs. In the past, scholars had different opinions about the causes of tolerance and the factors that affected the occurrence of tolerance. In 1928, Chen Kehui put forward the theory of “point-blocking” to explain the acute tolerance of ephedrine. This hypothesis has won the support of many scholars. In addition, there are some