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研究表明扩张型心肌病发生发展中自身免疫机制起着不可忽视的作用。实验性自身免疫性心肌炎/自身免疫性心肌病(EAM/EAC)动物模型的诱导,进一步阐明了其具体机制。EAM/EAC动物模型的诱导方式经历了以心肌肌球蛋白、自身抗原表位、负载自身抗原表位的免疫活性细胞的三个阶段,伴随的是对扩张型心肌病中自身免疫机制致病作用认识的进一步深化。
Studies have shown that the development of autoimmune mechanisms in the development of dilated cardiomyopathy play a non-negligible role. The induction of experimental autoimmune myocarditis / autoimmune cardiomyopathy (EAM / EAC) animal models further elucidates its specific mechanism. The induction of EAM / EAC animal models has undergone three stages of myocardial myosin, autoantigen epitopes, and autoimmune cells that carry autoantigen epitopes, with pathogenic effects on autoimmune mechanisms of dilated cardiomyopathy Further deepening of understanding.