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0引言肿瘤的形成和转移不仅与蛋白酶激活受体-2(protease-activated receptor-2,PAR-2)有关,还与组织因子(tissue factor,TF)密切相关。PAR-2与TF在肿瘤形成和转移时的作用越来越被重视,成为肿瘤治疗研究方面的新靶点,现就PAR-2与TF和肿瘤的关系综述如下。1蛋白酶激活受体-2(PA
0 Introduction Tumor formation and metastasis are not only related to the protease-activated receptor-2 (PAR-2), but also to the tissue factor (TF). The role of PAR-2 and TF in tumor formation and metastasis is gaining more and more attention and has become a new target in tumor therapy research. The relationship between PAR-2 and TF and tumor is summarized as follows. 1 Protease Activated Receptor-2 (PA