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研究角膜胶原膜的制做方法及其在单纯疱疹病毒性角膜炎（ＨＳＫ）治疗中的应用。从猪巩膜中提取胶原采用离心干燥成膜法制成角膜胶原膜，在无环鸟苷药液内浸泡后用于治疗单纯疱疹病毒性角膜炎。结果应用浸泡无环鸟苷（ＡＣＶ）药液的胶原膜治疗组病灶平均愈合时间为９．４５天，局部滴无环鸟苷药液组病灶愈合平均时间为１４．３６天，两组治愈率和有效率分别为９０．６３％、６５．６３％和９６．８８％，８１．２５％差异显著（ｐ＜０．０５）。可见浸泡无环鸟苷药液后的胶原膜在单纯疱疹病毒性角膜炎的治疗中将具有较好的应用前景。
To study the preparation of corneal collagen membrane and its application in the treatment of herpes simplex virus keratitis (HSK). Collagen was extracted from porcine sclera and the corneal collagen membrane was prepared by centrifugal drying and then used to treat herpes simplex keratitis after soaking in acyclovir solution. Results The average healing time of the lesions treated with ACV solution was 9.45 days, and the average time for the healing of the lesions was 14.36 days in the local acyclovir solution group. The cure rates of the two groups And the effective rates were 90.63%, 65.63% and 96.88%, respectively, with a significant difference of 81.25% (p <0.05). It can be seen that the collagen membrane soaked in acyclovir solution will have a good application prospect in the treatment of herpes simplex virus keratitis.