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目的：探讨氟西汀联合抗精神病药物治疗伴有强迫症状的精神分裂症患者的临床效果。方法：选取2016年1月-2016年11月我院收治的患有强迫症状的精神分裂患者88例，将患者随机分为两组，每组44例，对照组患者进行常规精神分裂疾病药物治疗，研究组进行氟西汀联合抗精神病药物治疗，一段时间治疗后，对两组患者的治疗效果进行统计分析。结果：研究组的治疗效果显著高于对照组（P<0.05）。结论：对伴有强迫症状的精神分裂症患者使用氟西汀联合抗精神病药物治疗效果显著，有助于患者的康复。“,”objective: to study the fuoxetine combined therapy with antipsychotic drugs with the clinical effect of forcing the symptoms of schizophrenia patients. Selection methods: January2016 - November2016, our hospital88 cases sufering from symptoms of schizophrenia patients, the patients were randomly divided into two groups, each group of44 cases, control group patients with conventional schizophrenia disease, drug treatment group with fuoxetine combined therapy with antipsychotic drugs, for a period of time after treatment, the treatment effect of two groups of patients were analyzed. Results: the treatment group effect is significantly higher than control group (P <0.05). Conclusion: the forced symptoms of schizophrenia patients with fluoxetine combined therapy with antipsychotic drugs efect is remarkable, is helpful for the recovery of patients.