神经蛋白聚糖是中枢神经系统一种重要的硫酸软骨素蛋白聚糖 ,其在神经组织发育期调节细胞与细胞和细胞与基质的相互作用方面发挥了重要作用。神经蛋白聚糖在幼年期有高水平的表达 ,但在成年期很难检测到。脑损伤后 ,神经蛋白聚糖在胶质瘢痕中的表达明显增加 ,据认为可阻止轴突再生。 Neurocan is an important chondroitin sulfate proteoglycan in the central nervous system that plays an important role in the regulation of cell-cell and cell-matrix interactions during the development of the nervous system. Neurocan has a high level of expression at infancy, but is difficult to detect in adulthood. After brain injury, neurocan expression was significantly increased in glial scar, which is thought to prevent axon regeneration.