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目的探讨血清尿酸和胆红素与急性冠状动脉综合征(ACS)的关系。方法分别测定60例急性冠脉综合症患者(ACS组)、50例稳定型心绞痛患者(SAP组)、60例冠状动脉造影阴性者(对照组)的血清尿酸、胆红素水平,进行对比分析。结果ACS组血清尿酸水平显著高于SAP组(P<0.01)和对照组(P<0.001),总胆红素ACS组显著低于对照组(P<0.001),间接胆红素ACS组显著低于SAP组和对照组,直接胆红素显著高于SAP组和对照组。结论尿酸和胆红素可能参与了ACS的发病过程。
Objective To investigate the relationship between serum uric acid, bilirubin and acute coronary syndrome (ACS). Methods The levels of serum uric acid and bilirubin in 60 patients with acute coronary syndrome (ACS group), 50 patients with stable angina pectoris (SAP group) and 60 patients with coronary artery angiography (control group) were measured and compared . Results Serum uric acid in ACS group was significantly higher than that in SAP group (P <0.01) and control group (P <0.001), total bilirubin ACS group was significantly lower than that in control group (P <0.001), indirect bilirubin ACS group was significantly lower In SAP group and control group, direct bilirubin was significantly higher than SAP group and control group. Conclusion Uric acid and bilirubin may be involved in the pathogenesis of ACS.