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目的基于汶川和芦山地震伤病员的实际药品使用情况,对比分析四川大学华西医院在汶川地震和芦山地震中应急药品使用的合理性。方法以用药频度(defined daily dose system,DDDs)和药物利用指数(drug utilization index,DUI)为评价指标,采用Excel软件进行数据录入,统计分析两次地震后1个月内四川大学华西医院应急药品的使用合理性。结果汶川地震和芦山地震后1个月内,该院收治伤病员数分别为1 839人和488人。两次地震后1个月内,住院人数与药品DDDs波动趋势基本一致,但芦山地震两者趋势的一致性更好。汶川地震应急救援中,各类药理分类DDDs排名靠前的60种药品中,注射剂型多于非注射剂型药品(70.0%vs.30.0%);DUI值=1者仅10.0%,DUI值<1者占28.3%(提示用药不足),DUI值>1者占61.7%(提示用药过度);60种药品DUI均值为1.61。芦山地震应急救援中,各类药理分类DDDs排名靠前的60种药品中,注射剂型多于非注射剂型药品(63.3%vs.36.7%);DUI值=1者仅15.0%,DUI值<1者占38.3%,DUI值>1者占46.7%;60种药品DUI均值为1.30。结论根据DUI计算结果,芦山地震后1个月内药品供应的及时性与合理性均较汶川地震更好。但采用常态下DUI判断应急药品使用合理性尚需进一步证实。
OBJECTIVE: To analyze the rationality of using emergency medicines in West China Hospital of Sichuan University during Wenchuan Earthquake and Lushan Earthquake on the basis of the actual drug use of the wounded and sick in Wenchuan and Lushan earthquakes. Methods DDDs and drug utilization index (DUI) were used as evaluation indexes and data were input by Excel software. Statistical analysis was performed within one month after the occurrence of the two earthquakes in West China Hospital of Sichuan University Rational use of medicines. Results Within 1 month after Wenchuan Earthquake and Lushan Earthquake, the number of wounded and sick in the hospital was 1,839 and 488, respectively. Within one month after the two earthquakes, the trend of DDDs in hospitalization was basically the same as the number of inpatients, but the trend of consistency between the two Lushan earthquakes was even better. In Wenchuan earthquake emergency rescue, the top 60 DDDs in pharmacological classification were more injections than in non-injection drugs (70.0% vs. 30.0%); DUI value was only 10.0% in 1, DUI value was less than 1 Accounting for 28.3% (suggesting lack of medication), DUI value> 1 accounted for 61.7% (suggesting overdose); 60 drugs DUI mean 1.61. In Lushan earthquake emergency rescue, the top 60 DDDs in pharmacological classification were more injections than non-injection drugs (63.3% vs.36.7%); the DUI value was only 15.0% for DQ value of 1, and the DUI value was less than 1 Accounting for 38.3%, DUI value> 1 accounted for 46.7%; 60 drugs DUI mean 1.30. Conclusion According to the DUI calculation results, the timeliness and rationality of drug supply within 1 month after Lushan Earthquake are better than that of the Wenchuan earthquake. However, the use of DUI to determine the rationality of using emergency drugs needs to be further confirmed.