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目的通过检测胎儿纤维连接蛋白(FFN),研究支原体宫颈炎和羊水胎粪污染的关系,为预测胎儿窘迫提供新方法。方法采用酶联免疫吸附法(ELISA)对支原体宫颈炎患者120例(研究组),健康孕妇81例(对照组)进行宫颈阴道分泌物FFN检测,以FFN≥50ng/mL为判断阳性标准。结果研究组FFN阳性患者75例,阳性率62.5%(75/120),对照组FFN阳性患者31例,阳性率38.2%(31/81);研究组羊水胎粪污染18例,阳性率24%(18/75),对照组羊水胎粪污染2例,阳性率4%(2/50)。两组比较均有显著性差异(P<0.05)。结论FFN与支原体宫颈炎有关系,对预测羊水胎粪污染及早期治疗胎儿窘迫有价值。
Objective To investigate the relationship between mycoplasma cervicitis and meconium-stained amniotic fluid by detecting fetal fibronectin (FFN) and provide a new method for predicting fetal distress. Methods 120 cases of mycoplasma cervicitis (study group) and 81 healthy pregnant women (control group) were examined by enzyme-linked immunosorbent assay (ELISA). FFN≥50 ng / mL was used as the positive standard. Results The positive rate of FFN in study group was 75.5% (75/120), the positive rate was 38.2% (31/81) in control group. The positive rate of amniotic fluid meconium in study group was 18%, the positive rate was 24% (18/75), 2 cases of amniotic fluid meconium-stained in control group, the positive rate was 4% (2/50). There was significant difference between the two groups (P <0.05). Conclusion FFN and mycoplasma cervicitis have a relationship, the prognosis of amniotic fluid meconium pollution and early treatment of fetal distress valuable.